Caspase 2

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Also Known As:

Caspase 2 Subunit p12; Caspase 2 Subunit p13; Caspase 2 Subunit p18; Caspase-2; ICH-1 Protease; Pro-Caspase-2; Procaspase-2; ICH 1 Protease; Pro Caspase 2; Procaspase 2

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        Caspases: 9379
        Initiator Caspases: 34
        Caspase 2: 307
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        Caspases: 9379
        Initiator Caspases: 34
        Caspase 2: 307
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Caspases: 9379
        Initiator Caspases: 34
        Caspase 2: 307

T G Oliver Selected Research

T G Oliver Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure